PAPSimTM is a comprehensive package for simulating asphaltene precipitation in oil industry. Based on the PAPSimTMinbuilt engines in PVT, asphaltene and optimizer modules, PAPSimTM can simulate asphaltene precipitation in natural depletion and fluid injection processes. In addition, the effects of temperature, pressure and composition changes on the asphaltene precipitation can be simulated in PAPSimTM. Oil and gas phase behaviors are modeled by a powerful compositional CEOS based engine. The asphaltene phase behavior is simulated by two polymer solution models, MMFH and MFH in PAPSimTM. Simulated annealing procedure is used in non-linear regression to adjust asphaltene model parameters with experimental data.